Differential Metabolic and Biological Profiles of Lychnophora ericoides Mart. (Asteraceae) from Different Localities in the Brazilian “campos rupestres”

نویسندگان

  • Leonardo Gobbo-Neto
  • Thais Guaratini
  • Cláudia Pessoa
  • Manoel O. de Moraes
  • Letícia V. Costa-Lotufo
  • Roberto F. Vieira
  • Norberto P. Lopes
چکیده

Este artigo descreve a caracterização por CLAE-DAD-EM/EM e CLAE-DEC dos perfis de metabólitos secundários de extratos das folhas de Lychnophora ericoides Mart. de diferentes procedências e suas propriedades citotóxicas e antioxidantes. Extratos foliares de populações representando sete diferentes localidades foram avaliados quanto à atividade antioxidante pelo sistema DPPH e à atividade citotóxica em três linhagens tumorais. Os extratos foram eletroquimicamente caracterizados por CLAE-DEC e seus metabólitos secundários majoritários foram identificados por CLAE-DAD-EM e CLAE-DAD-EM/EM. Um metabolismo secundário defensivo amplificado, juntamente com as mais altas bioatividades antioxidantes e citotóxicas, foi encontrado para as plantas coletadas na interface entre dois tipos de vegetação. Estes resultados fornecem apoio adicional para a hipótese de que plantas ocorrendo na interface entre dois ecossistemas podem ser estimuladas a amplificar sua produção e armazenamento de metabólitos secundários defensivos, devido ao maior número de influências ambientais.

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تاریخ انتشار 2010